Partnering with Patient Organizations
We are proud to support and collaborate with the patient advocacy organizations that serve as lifelines for families affected by congenital hyperinsulinism (cHI) and tumor hyperinsulinism.
The organizations below were each founded by caregivers and patients whose lives have been impacted by hyperinsulinism, and they play a vital role in connecting their respective communities to education, research, clinical care, and support. Their work informs and inspires our own, and we are honored to stand alongside them in advancing their mission and amplifying their impact.
Understanding HI

Congenital Hyperinsulinism

Tumor Hyperinsulinism
About Ersodetug
Ersodetug is an insulin receptor modulating antibody, a type of treatment created using the body’s own targeting system to attach to the side of the insulin receptor (a part of your cells that helps control blood sugar) and makes it harder for certain proteins, like insulin or insulin-like growth factor 2 (IGF-2), to lower blood sugar too much. This action may help keep blood sugar levels in a more stable, healthier range.
Compassionate Use
When no approved treatments are available, some patients may qualify for Compassionate Use, also called an Expanded Access Program (EAP). Rezolute supports EAPs to help patients with serious conditions access investigational therapies like ersodetug. An investigational therapy is one that is being studied but has not yet been approved for any use by any health authority.
Our EAP is designed for patients who benefited from ersodetug during clinical trials and wish to continue treatment, or for those with severe, frequent low blood sugar due to high insulin levels who have no other options.
If you think you may qualify, talk to your healthcare provider or contact us at medical-affairs@rezolutebio.com.
Ersodetug is an investigational drug candidate. The FDA has not determined that ersodetug is safe or effective. No indication(s), warnings, precautions, adverse reactions, dosage or administration information for ersodetug have been approved by the FDA. This video depicts the favorable results of ersodetug use for a single patient. It is not intended to guarantee or promote that ersodetug will provide similar results for other subjects participating in the ersodetug Phase III clinical trial or Expanded Access Program.
This video, may contain certain forward-looking statements regarding our prospective performance and strategies within the meaning of Section 27A of the Securities Act and Section 21E of the Securities Exchange Act of 1934, as amended. We intend such forward-looking statements to be covered by the safe harbor provisions for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995 and are including this statement for purposes of said safe harbor provisions. Forward-looking statements, which are based on certain assumptions and describe future plans, strategies, and expectations of Rezolute, are generally identified by use of words such as “anticipate,” “believe,” “estimate,” “expect,” “intend,” “plan,” “project,” “prove,” “potential,” “seek,” “strive,” “try,” or future or conditional verbs such as “predict,” “could,” “may,” “likely,” “should,” “will,” “would,” or similar expressions. Our ability to predict results or the actual effects of our plans or strategies is inherently uncertain. Accordingly, actual results may differ materially from anticipated results. Viewers are cautioned not to place undue reliance on these forward-looking statements, which speak only as an individual patient. Except as required by applicable law or regulation, Rezolute undertakes no obligation to update these forward-looking statements to reflect events or circumstances that occur after the date on which such statements were made. Important factors that may cause such a difference include any other factors discussed in our filings with the SEC, including the Risk Factors contained in the Rezolute’s Annual Report on Form 10-K and Quarterly Reports on Form 10-Q, which are available at the SEC’s website at www.sec.gov.
You are urged to consider these factors carefully in evaluating the forward-looking statements in this release and are cautioned not to place undue reliance on such forward-looking statements, which are qualified in their entirety by this cautionary statement. This video shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of these securities in any state or other jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or other jurisdiction.